Tuesday, March 31, 2009

Saquinavir Mesylate




Saquinavir Mesylate may be available in the countries listed below.


Ingredient matches for Saquinavir Mesylate



Saquinavir

Saquinavir Mesylate (BANM, USAN) is known as Saquinavir in the US.

International Drug Name Search

Glossary

BANMBritish Approved Name (Modified)
USANUnited States Adopted Name

Click for further information on drug naming conventions and International Nonproprietary Names.

Monday, March 23, 2009

Biaminthic




Biaminthic may be available in the countries listed below.


In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Biaminthic



Levamisole

Levamisole hydrochloride (a derivative of Levamisole) is reported as an ingredient of Biaminthic in the following countries:


  • France

International Drug Name Search

Monday, March 16, 2009

Bromfed DM


Generic Name: brompheniramine, dextromethorphan, and pseudoephedrine (brom fen EER a meen, dex troe me THOR fan, soo doe e FED rin)

Brand Names: Allanhist PDX Drops, Anaplex DM, Anaplex DMX, Andehist DM NR Syrup, Brom Tann, Bromaline DM, Bromdex D, Bromfed DM, Bromhist PDX, Bromhist-DM Drops, Bromophed-DX, Bromph DM, Bromplex DM, BroveX PSE DM, Dallergy DM, EndaCof-DM, Histacol BD Drops, Myphetane DX Cough, Neo DM, PBM Allergy, Pediahist DM Drops, ProHist DM, Q-Tapp DM, Resperal-DM Drops, Robitussin Allergy & Cough, Sildec DM


What is Bromfed DM (brompheniramine, dextromethorphan, and pseudoephedrine)?

Brompheniramine is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.


Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.


Pseudoephedrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).


The combination of brompheniramine, dextromethorphan, and pseudoephedrine is used to treat runny or stuffy nose, sneezing, itching, watery eyes, cough, and sinus congestion caused by allergies, the common cold, or the flu.


This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Brompheniramine, dextromethorphan, and pseudoephedrine may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Bromfed DM (brompheniramine, dextromethorphan, and pseudoephedrine)?


Dosage - adults and children 12 years and over: 2 teaspoonfuls every 4 hours. Children 6 to under 12 years: 1 teaspoonful every 4 hours. Children 2 to under 6 years of age: half a teaspoonful every 4 hours. Infants 6 months to under 2 years of age: dosage to be established by a physician. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. You should not use this medication if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate. Do not use cough or cold medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Do not use cough or cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

What should I discuss with my healthcare provider before taking Bromfed DM (brompheniramine, dextromethorphan, and pseudoephedrine)?


Do not use cough or cold medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. You should not use this medication if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate. Do not use cough or cold medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid.

Ask a doctor or pharmacist if it is safe for you to take this medication if you have:



  • a blockage in your digestive tract (stomach or intestines), a colostomy or ileostomy;




  • diabetes;




  • liver or kidney disease;




  • epilepsy or other seizure disorder;




  • cough with mucus, or cough caused by emphysema or chronic bronchitis;




  • enlarged prostate or urination problems;




  • low blood pressure;




  • pheochromocytoma (an adrenal gland tumor); or




  • if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).




FDA pregnancy category C. It is not known whether this medication will harm an unborn baby. Do not use cough or cold medicine without medical advice if you are pregnant. This medicine may pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use cough or cold medicine without medical advice if you are breast-feeding a baby.

How should I take Bromfed DM (brompheniramine, dextromethorphan, and pseudoephedrine)?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Cough or cold medicine is usually taken only for a short time until your symptoms clear up.


Dosage - adults and children 12 years and over: 2 teaspoonfuls every 4 hours. Children 6 to under 12 years: 1 teaspoonful every 4 hours. Children 2 to under 6 years of age: half a teaspoonful every 4 hours. Infants 6 months to under 2 years of age: dosage to be established by a physician. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Do not take for longer than 7 days in a row. Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache or skin rash.


Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.


If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken a cough or cold medicine within the past few days. Store at room temperature away from moisture and heat. Do not freeze.

What happens if I miss a dose?


Since cough or cold medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.


What should I avoid while taking Bromfed DM (brompheniramine, dextromethorphan, and pseudoephedrine)?


This medicine may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Drinking alcohol can increase certain side effects of this medication. Ask a doctor or pharmacist before using any other cold, allergy, cough, or sleep medicine. Antihistamines, cough suppressants, and decongestants are contained in many combination medicines. Taking certain products together can cause you to get too much of a certain drug. Check the label to see if a medicine contains an antihistamine, cough suppressant, or decongestant.

Avoid taking this medication if you also take diet pills, caffeine pills, or other stimulants (such as ADHD medications). Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.


Avoid becoming overheated or dehydrated during exercise and in hot weather. This medication can decrease sweating and you may be more prone to heat stroke.

Bromfed DM (brompheniramine, dextromethorphan, and pseudoephedrine) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medicine and call your doctor at once if you have a serious side effect such as:

  • fast, slow, or uneven heart rate;




  • severe headache, mood changes, hallucinations;




  • severe dizziness or anxiety, feeling like you might pass out;




  • tremor, seizure (convulsions);




  • easy bruising or bleeding, unusual weakness;




  • fever;




  • urinating less than usual or not at all;




  • feeling short of breath; or




  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, uneven heartbeats, seizure).



Less serious side effects may include:



  • mild headache;




  • mild dizziness, drowsiness;




  • dry mouth, nose, or throat;




  • nausea, diarrhea, constipation, upset stomach;




  • feeling nervous, restless, or irritable;




  • blurred vision; or




  • sleep problems (insomnia).



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Bromfed DM (brompheniramine, dextromethorphan, and pseudoephedrine)?


Ask a doctor or pharmacist before using this medicine if you regularly use other medicines that make you sleepy (such as narcotic pain medication, sedatives, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by brompheniramine or dextromethorphan.


Ask a doctor or pharmacist if it is safe for you to take this medication if you are also using any of the following drugs:



  • atropine (Atreza, Sal-Tropine);




  • benztropine (Cogentin);




  • topiramate (Topamax);




  • zonisamide (Zonegran);




  • an antidepressant such as citalopram (Celexa), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), paroxetine (Paxil, Pexeva), sertraline (Zoloft), venlafaxine (Effexor), and others;




  • anti-nausea medications such as belladonna (Donnatal), dimenhydrinate (Dramamine), droperidol (Inapsine), methscopolamine (Pamine), or scopolamine (Transderm Scop);




  • bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), solifenacin (Vesicare), tolterodine (Detrol), or Urogesic Blue;




  • bronchodilators such as ipratropium (Atrovent) or tiotropium (Spiriva);




  • irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Hyomax), or propantheline (Pro Banthine); or




  • ulcer medicine such as glycopyrrolate (Robinul) or mepenzolate (Cantil).



This list is not complete and other drugs may interact with brompheniramine, dextromethorphan, and pseudoephedrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Bromfed DM resources


  • Bromfed DM Side Effects (in more detail)
  • Bromfed DM Use in Pregnancy & Breastfeeding
  • Bromfed DM Drug Interactions
  • Bromfed DM Support Group
  • 0 Reviews for Bromfed DM - Add your own review/rating


  • Bromfed DM Prescribing Information (FDA)

  • Bromfed DM Elixir MedFacts Consumer Leaflet (Wolters Kluwer)

  • Anaplex DMX Suspension MedFacts Consumer Leaflet (Wolters Kluwer)

  • Bromdex D Prescribing Information (FDA)

  • Myphetane DX Prescribing Information (FDA)

  • Neo DM Suspension MedFacts Consumer Leaflet (Wolters Kluwer)

  • Resperal-DM Drops MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Bromfed DM with other medications


  • Cough and Nasal Congestion


Where can I get more information?


  • Your pharmacist can provide more information about brompheniramine, dextromethorphan, and pseudoephedrine.

See also: Bromfed DM side effects (in more detail)


Friday, March 13, 2009

Eubrain




Eubrain may be available in the countries listed below.


Ingredient matches for Eubrain



Piracetam

Piracetam is reported as an ingredient of Eubrain in the following countries:


  • Taiwan

International Drug Name Search

Wednesday, March 11, 2009

Loperamid AL




Loperamid AL may be available in the countries listed below.


Ingredient matches for Loperamid AL



Loperamide

Loperamide hydrochloride (a derivative of Loperamide) is reported as an ingredient of Loperamid AL in the following countries:


  • Germany

International Drug Name Search

Monday, March 9, 2009

Revlimid



Pronunciation: LEN-a-LID-oh-mide
Generic Name: Lenalidomide
Brand Name: Revlimid

Revlimid may cause severe birth defects or death of the fetus if used during pregnancy. Revlimid is similar to thalidomide, which causes life-threatening birth defects.


Females who are able to become pregnant and who take Revlimid:


  • must not become pregnant;

  • must avoid sexual contact with men or use at least 2 forms of effective birth control for 4 weeks before starting Revlimid, while taking Revlimid, during dose interruptions, and for 4 weeks after stopping Revlimid;

  • must have a negative pregnancy test 10 to 14 days before starting Revlimid and again within 24 hours before starting Revlimid; and

  • must have a pregnancy test every week for the first 4 weeks after starting Revlimid and then every 2 to 4 weeks thereafter while using Revlimid.

Women who experience abnormal menstrual bleeding, miss their menstrual period, become pregnant, or suspect for any reason they may be pregnant while taking Revlimid must stop taking it and contact their doctor immediately.


Males who take Revlimid must either:


  • avoid sexual contact with women who are pregnant or could become pregnant while taking Revlimid and for 4 weeks after stopping Revlimid; OR

  • use a latex condom during sexual contact with women who are pregnant or could become pregnant for as long as they are taking Revlimid and for 4 weeks after stopping Revlimid, even if they have had a successful vasectomy.

Men who have unprotected sexual contact with a woman who is pregnant or may become pregnant or who think for any reason that their sexual partner may be pregnant should contact their doctor immediately.


All patients who take Revlimid:


  • It is not known if Revlimid passes into semen. Female partners of men taking Revlimid should call their doctor if they become pregnant.

  • All patients must receive and understand all oral and written warnings about the risks of using Revlimid.

  • All patients must be able to follow the instructions for using Revlimid and for using effective birth control methods if they are sexually active.

  • Revlimid may cause an increased risk of blood clots in the veins and lungs. Call your doctor right away if you experience shortness of breath; chest pain; or pain, redness, tenderness, or swelling in the arms or legs.

  • Revlimid often lowers the number of white blood cells and platelets in the blood. Call your doctor right away if you experience unusual bleeding or bruising, fever, chills, or sore throat.

  • Blood counts should be checked each week for the first 8 weeks after starting Revlimid and at least once per month thereafter. If low blood counts develop, it may be necessary to lower the dose or stop treatment. Sometimes blood transfusions and treatment with other medicines may be necessary. Keep all doctor and lab appointments while using Revlimid.




Revlimid is used for:

Treating anemia in patients who have certain types of myelodysplastic syndrome (MDS). It is also used along with dexamethasone to treat a certain type of cancer (multiple myeloma) in certain patients.


Revlimid is an immunomodulatory medicine. Exactly how it works is not known.


Do NOT use Revlimid if:


  • you are allergic to any ingredient in Revlimid

  • you are pregnant, planning to become pregnant, could become pregnant, or become pregnant during treatment with Revlimid

  • you have had a severe allergic reaction (eg, rash; hives; hoarseness; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue) or a severe rash (eg, red, swollen, blistered, or peeling skin) from Revlimid or thalidomide in the past

Contact your doctor or health care provider right away if any of these apply to you.



Before using Revlimid:


Some medical conditions may interact with Revlimid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a tumor, cancer, kidney problems, certain hereditary problems (glucose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption), low white blood cell levels, or low platelet counts or if you receive dialysis

  • if you have an infection, blood electrolyte problems, high blood pressure, or a history of blood clots or heart problems (eg, irregular heartbeat, heart attack)

Some MEDICINES MAY INTERACT with Revlimid. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Erythropoietic agents (eg, erythropoietin), estrogens (eg, estrogen, estradiol), progestins (eg, medroxyprogesterone), or medicines that contain estrogens or progestins (eg, birth control pills) because the risk of developing blood clots may be increased

  • Digoxin because the risk of its side effects may be increased by Revlimid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Revlimid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Revlimid:


Use Revlimid as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Revlimid comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Revlimid refilled.

  • Revlimid can only be prescribed and dispensed through a special program. Make sure you understand all warnings and instructions for using Revlimid. Ask your doctor or pharmacist if you have any questions about this program or the use of Revlimid.

  • Take Revlimid by mouth with or without food.

  • Swallow Revlimid whole with water. Do not break, crush, or chew before swallowing.

  • Women who are able to become pregnant (including those who have started menopause within the last 24 months) must use at least 2 methods of effective birth control while taking Revlimid, unless they are not sexually active. These birth control methods must be used for at least 4 weeks before starting Revlimid, while taking Revlimid, during dose interruptions, and for 4 weeks after stopping Revlimid. Talk with your doctor about which methods of effective birth control may be appropriate for you.

  • Men who take Revlimid must always use a latex condom during any sexual contact with a woman who is pregnant or could become pregnant. Do this for as long as you are taking Revlimid and for 4 weeks after you stop taking it. This includes men who have had a vasectomy.

  • Do not open the capsules or handle them more than needed. If you touch a broken capsule or the medicine inside of the capsule, wash the area with soap and water.

  • If you miss a dose of Revlimid and it has been less than 12 hours since the missed dose, take it as soon as you remember. If it has been more than 12 hours since the missed dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Revlimid.



Important safety information:


  • Revlimid may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Revlimid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Revlimid may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.

  • Revlimid may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.

  • Revlimid may increase the risk of blood clots in certain patients. Tell your doctor at once if you notice shortness of breath; chest pain; or pain, redness, tenderness, or swelling of an arm or leg.

  • Patients with cancer who take Revlimid have a risk of developing a serious and possibly fatal condition called tumor lysis syndrome (TLS). Contact your doctor right away if you develop symptoms such as fast or irregular heartbeat; fainting; decreased urination; muscle weakness or cramps; nausea, vomiting, diarrhea, or loss of appetite; or sluggishness.

  • Do not donate semen, sperm, or blood while taking Revlimid or within 4 weeks after stopping Revlimid.

  • If you are using a hormonal contraceptive (eg, birth control pills) to prevent pregnancy, inform your doctor if you also take an HIV protease inhibitor (eg, ritonavir); griseofulvin, rifampin, rifabutin, penicillin, amoxicillin, ampicillin, or other antibiotic medicines; St. John's wort; modafinil; phenytoin; or carbamazepine. These medicines may decrease the effectiveness of hormonal contraceptives.

  • Lab tests, including pregnancy tests and complete blood cell counts, may be performed while you use Revlimid. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Revlimid with caution in the ELDERLY; they may be more sensitive to its effects.

  • Revlimid should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: Use of Revlimid during pregnancy may cause severe birth defects and death of the fetus. If you think you may be pregnant, miss your menstrual period, experience unusual menstrual bleeding, or stop using birth control, contact your doctor right away. If you become pregnant while using Revlimid, consult an obstetrician/gynecologist experienced in reproductive toxicity. It is not known if Revlimid is found in breast milk. Do not breast-feed while taking Revlimid.


Possible side effects of Revlimid:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Back pain; constipation; cough; diarrhea; dizziness; dry mouth or skin; headache; increased sweating or night sweats; loss of appetite; mild stomach pain; nausea; sluggishness; stuffy or runny nose; taste changes; tiredness; trouble sleeping; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; hoarseness; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in the stools or vomit; burning, numbness, or tingling; chest pain; confusion; dark urine; depression; difficulty swallowing; fainting; fast, slow, or irregular heartbeat; fever, chills, or sore throat; joint pain; muscle pain, weakness, or cramps; one-sided weakness; pain, numbness, tingling, tenderness, redness, or swelling of the arms or legs; painful or difficult urination; red, swollen, blistered, or peeling skin; reduces senses of touch; severe or persistent headache, dizziness, or stomach pain; severe tiredness or weakness; shortness of breath; slurred speech; swelling of the hands, ankles, or feet; tremor; unusual bruising or bleeding; vision problems.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Revlimid side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Revlimid:

Store Revlimid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Revlimid out of the reach of children and away from pets.


General information:


  • If you have any questions about Revlimid, please talk with your doctor, pharmacist, or other health care provider.

  • Revlimid is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Revlimid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Revlimid resources


  • Revlimid Side Effects (in more detail)
  • Revlimid Use in Pregnancy & Breastfeeding
  • Revlimid Drug Interactions
  • Revlimid Support Group
  • 1 Review for Revlimid - Add your own review/rating


  • Revlimid Prescribing Information (FDA)

  • Revlimid Consumer Overview

  • Revlimid Monograph (AHFS DI)

  • Revlimid Advanced Consumer (Micromedex) - Includes Dosage Information

  • Lenalidomide Professional Patient Advice (Wolters Kluwer)



Compare Revlimid with other medications


  • Anemia
  • Multiple Myeloma