Nicotrol NS Spray

Pronunciation: NIK-oh-teen
Generic Name: Nicotine
Brand Name: Nicotrol NS

Nicotrol NS Spray is used for:

Helping you to quit smoking.

Nicotrol NS Spray is a smoking deterrent. It works by providing low levels of nicotine, which may help you to quit smoking by lessening the physical signs of withdrawal symptoms.

Do NOT use Nicotrol NS Spray if:

• you are allergic to any ingredient in Nicotrol NS Spray


• you have had a recent heart attack


• you have persistent nose problems (eg, allergies, runny nose, nasal polyps, sinusitis) or severe asthma


• you have severe or worsening chest pain or a severely irregular heartbeat


• you continue to smoke, chew tobacco, use snuff, or any other nicotine-containing products

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nicotrol NS Spray:

Some medical conditions may interact with Nicotrol NS Spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have chest pain (eg, angina), heart problems (eg, coronary artery disease, irregular heartbeat), a history of heart attack, high blood pressure, breathing problems (eg, asthma), an overactive thyroid, an ulcer, a tumor on your adrenal gland (pheochromocytoma), diabetes, kidney or liver problems, or blood vessel problems (eg, Buerger disease, Raynaud phenomena)

Some MEDICINES MAY INTERACT with Nicotrol NS Spray. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Acetaminophen, adrenergic antagonists (eg, prazosin), beta-blockers (eg, labetalol, propranolol), caffeine, imipramine, insulin, oxazepam, pentazocine, or theophylline because the risk of their side effects may be increased when you stop smoking


• Adrenergic agonists (eg, isoproterenol, phenylephrine) because their effectiveness may be decreased when you stop smoking

This may not be a complete list of all interactions that may occur. Ask your health care provider if Nicotrol NS Spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Nicotrol NS Spray:

Use Nicotrol NS Spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Nicotrol NS Spray. Talk to your pharmacist if you have questions about this information.


• Tilt your head back slightly while using Nicotrol NS Spray.


• Spray Nicotrol NS Spray in your nose whenever you feel the urge to smoke.


• Do not sniff, swallow, or inhale through the nose while the spray is being used


• Do not use more than 1 spray in each nostril for a dose without checking with your doctor.


• Do not exceed 5 doses per hour or 40 doses per day.


• If you miss a dose of Nicotrol NS Spray, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Nicotrol NS Spray.

Important safety information:

• Nicotrol NS Spray may cause dizziness, lightheadedness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Nicotrol NS Spray with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Tell your doctor or dentist that you take Nicotrol NS Spray before you receive any medical or dental care, emergency care, or surgery.


• Be careful while opening and closing the container of medicine. The container may break if it is dropped. If this happens, clean up the spill immediately with an absorbent cloth or paper towel. Avoid contact with the skin. Pick up broken glass carefully, using a broom. Wash the area several times. The absorbent material may be thrown away as household waste. If even a small amount of Nicotrol NS Spray contacts your skin, lips, eyes, or ears, immediately rinse the area with water only.


• Do NOT use Nicotrol NS Spray for longer than 6 months. If you still feel the need to use Nicotrol NS Spray after 6 months, check with your doctor.


• Do not smoke or use tobacco products while you are using Nicotrol NS Spray.


• Nicotrol NS Spray should be used as part of a larger program to help you stop smoking. If you need help choosing a program, talk with your health care provider.


• Diabetes patients - Nicotrol NS Spray may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Use Nicotrol NS Spray with caution in the ELDERLY; they may be more sensitive to its effects.


• Nicotrol NS Spray should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Nicotrol NS Spray may cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nicotrol NS Spray while you are pregnant. Nicotrol NS Spray is found in breast milk. If you are or will be breast-feeding while you use Nicotrol NS Spray, check with your doctor. Discuss any possible risks to your baby.

When used for long periods of time or at high doses, some people develop a need to continue taking Nicotrol NS Spray. This is known as DEPENDENCE or addiction.

Do not suddenly stop taking Nicotrol NS Spray without your doctor's approval. Stopping Nicotrol NS Spray suddenly may cause serious WITHDRAWAL symptoms. These may include: anxiety, craving, impaired concentration, increased appetite, irritability, nervousness, sleep disturbances, and weight gain.

Possible side effects of Nicotrol NS Spray:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Acne; back pain; burning or irritation of the mouth, nose, or eyes; changes in taste and smell; constipation; cough; earache; flushing of the face; gas; headache; hoarseness; indigestion; irritability; joint pain; mouth sores; nasal ulcers or blisters; nausea; nose bleed; numbness of the mouth; painful menstruation; runny nose; sinus irritation; sneezing; sore throat; stuffy nose; tingling; tooth disorder; watery eyes.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); fast or irregular heartbeat; lightheadedness; memory loss; severe dizziness or headache; shortness of breath; tightness in the chest; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Nicotrol NS side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include cold and clammy skin; confusion; diarrhea; difficulty breathing; dizziness; excessive saliva; fainting; headache; hearing and vision problems; nausea; rapid, weak, or irregular heartbeat; seizures; stomach pain; sweating; tremor; vomiting; weakness.

Proper storage of Nicotrol NS Spray:

Store Nicotrol NS Spray at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Nicotrol NS Spray out of the reach of children and away from pets.

General information:

• If you have any questions about Nicotrol NS Spray, please talk with your doctor, pharmacist, or other health care provider.


• Nicotrol NS Spray is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Nicotrol NS Spray. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Nicotrol NS resources

• Nicotrol NS Side Effects (in more detail)
• Nicotrol NS Use in Pregnancy & Breastfeeding
• Nicotrol NS Drug Interactions
• Nicotrol NS Support Group
• 0 Reviews for Nicotrol NS - Add your own review/rating

Compare Nicotrol NS with other medications

• Smoking Cessation

Luvox

Generic Name: fluvoxamine (floo VOX a meen)

Brand Names: Luvox, Luvox CR

What is Luvox (fluvoxamine)?

Fluvoxamine is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Fluvoxamine affects chemicals in the brain that may become unbalanced and cause obsessive-compulsive symptoms.

Fluvoxamine is used to treat social anxiety disorder (social phobia), or obsessive-compulsive disorders involving recurring thoughts or actions.

Fluvoxamine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Luvox (fluvoxamine)?

Do not take this medication if you are allergic to fluvoxamine, or if you are also taking alosetron (Lotronex), tizanidine (Zanaflex), thioridazine (Mellaril), pimozide (Orap), or an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam). Some of these medications can cause serious or life-threatening drug interactions when taken within 14 days before or after taking fluvoxamine.

You may have thoughts about suicide when you first start taking an this medication, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Video: Treatment for Depression

Treatments for depression are getting better everyday and there are things you can start doing right away.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself. There are many other medicines that can cause serious medical problems if you take them together with fluvoxamine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

What should I discuss with my healthcare provider before taking Luvox (fluvoxamine)?

You should not take this medication if you are allergic to fluvoxamine, or if you are also taking:

• 
  

  alosetron (Lotronex);

  
  


• 
  

  tizanidine (Zanaflex);

  
  


• 
  

  thioridazine (Mellaril);

  
  


• 
  

  pimozide (Orap); or

  
  


• 
  

  an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam).

  
  

Some of these medications can cause serious or life-threatening drug interactions when taken together with fluvoxamine. You must wait at least 14 days after stopping an MAO inhibitor before you can take fluvoxamine. After you stop taking fluvoxamine, you must wait at least 14 days before you can start taking an MAOI.

Before taking fluvoxamine, tell your doctor if you have:

• liver disease;


• 
  

  seizures or epilepsy;

  
  


• 
  

  bipolar disorder (manic depression); or

  
  


• 
  

  a history of drug abuse or suicidal thoughts.

  
  

If you have any of these conditions, you may need a dose adjustment or special tests to safely take fluvoxamine.

You may have thoughts about suicide when you first start taking fluvoxamine, especially if you are younger than 24 years old. Tell your doctor if you have symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

FDA pregnancy category C. This medication may cause serious or life-threatening lung problems in newborn babies whose mothers take the medication during pregnancy. However, you may have a relapse of symptoms if you stop taking fluvoxamine during pregnancy. If you are planning a pregnancy, or if you become pregnant while taking fluvoxamine, do not stop taking the medication without first talking to your doctor. Fluvoxamine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give fluvoxamine to anyone younger than 18 years old without the advice of a doctor.

How should I take Luvox (fluvoxamine)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Do not crush, chew, or open an extended-release capsule. Swallow the pill whole. Breaking or opening the pill may cause too much of the drug to be released at one time.

You may take fluvoxamine with or without food.

Do not stop using fluvoxamine without first talking to your doctor. You may have unpleasant side effects if you stop taking this medication suddenly. Store fluvoxamine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have taken too much of this medication. Overdose symptoms may include blurred vision, lack of coordination, extreme drowsiness, nausea and vomiting, fast heart rate, trouble breathing, fainting, and coma.

What should I avoid while taking Luvox (fluvoxamine)?

Avoid drinking alcohol, which can increase some of the side effects of fluvoxamine. Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, anxiety or depression can add to sleepiness caused by fluvoxamine. Tell your doctor if you regularly use any of these medicines.

Fluvoxamine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Luvox (fluvoxamine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have a serious side effect such as:

• 
  

  seizure (convulsions);

  
  


• 
  

  unusual thoughts or behavior;

  
  


• 
  

  anxiety, restlessness, memory problems, trouble concentrating, hallucinations, feeling like you might pass out;

  
  


• 
  

  high fever, chills or goose bumps, loss of coordination, overactive reflexes, stiff muscles; or

  
  


• 
  

  confusion, sweating, fast or uneven heartbeats, and rapid breathing.

  
  

Less serious side effects may include:

• 
  

  loss of appetite, weight loss;

  
  


• 
  

  dry mouth, mild nausea or upset stomach, diarrhea, constipation;

  
  


• 
  

  sleep problems (insomnia);

  
  


• 
  

  dizziness, drowsiness;

  
  


• 
  

  decreased sex drive, impotence, trouble having an orgasm; or

  
  


• 
  

  unusual dreams.

  
  

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Luvox (fluvoxamine)?

Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin and NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with fluvoxamine may cause you to bruise or bleed easily.

Many drugs can interact with fluvoxamine. Below is just a partial list. Tell your doctor if you are using:

• 
  

  carbamazepine (Carbatrol, Tegretol);

  
  


• 
  

  clopidogrel (Plavix);

  
  


• 
  

  clozapine (Clozaril, FazaClo);

  
  


• 
  

  a diuretic (water pill);

  
  


• 
  

  linezolid (Zyvox);

  
  


• 
  

  lithium (Lithobid, Eskalith);

  
  


• 
  

  methadone (Dolophine, Methadose);

  
  


• 
  

  mexiletine (Mexitil);

  
  


• 
  

  omeprazole (Prilosec);

  
  


• 
  

  phenytoin (Dilantin);

  
  


• 
  

  propranolol (Inderal, Inderal LA);

  
  


• 
  

  quinidine (Quinaglute, Quinidex, Quin-Release);

  
  


• 
  

  ramelteon (Rozerem);

  
  


• 
  

  St. John's wort;

  
  


• 
  

  tacrine (Cognex);

  
  


• 
  

  tramadol (Ultram);

  
  


• 
  

  tryptophan (also called L-tryptophan);

  
  


• 
  

  theophylline (Elixophyllin, Theo-24, Uniphyl);

  
  


• 
  

  a blood thinner such as warfarin (Coumadin);

  
  


• a sedative such as diazepam (Valium), alprazolam (Xanax), midazolam (Versed), or triazolam (Halcion);


• 
  

  almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig);

  
  


• 
  

  medicine to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), perphenazine (Trilafon), and others; or

  
  


• 
  

  an antidepressant such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Tofranil), and others.

  
  

This list is not complete and there are many other medicines that can cause serious medical problems if you take them together with fluvoxamine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

More Luvox resources

• Luvox Side Effects (in more detail)
• Luvox Use in Pregnancy & Breastfeeding
• Drug Images
• Luvox Drug Interactions
• Luvox Support Group
• 15 Reviews for Luvox - Add your own review/rating

• Luvox Advanced Consumer (Micromedex) - Includes Dosage Information


• Fluvoxamine MedFacts Consumer Leaflet (Wolters Kluwer)


• Fluvoxamine Prescribing Information (FDA)


• Fluvoxamine Maleate Monograph (AHFS DI)


• Luvox CR Prescribing Information (FDA)


• Luvox CR Extended-Release Capsules MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Luvox with other medications

• Anxiety and Stress
• Obsessive Compulsive Disorder

Where can I get more information?

• Your pharmacist can provide more information about fluvoxamine.

See also: Luvox side effects (in more detail)

Novarel

Generic Name: chorionic gonadotropin (Subcutaneous route, Intramuscular route, Injection route)

kor-ee-ON-ok goe-nad-oh-TROE-pin

Commonly used brand name(s)

In the U.S.

• Chorex


• Novarel


• Ovidrel


• Pregnyl


• Profasi

In Canada

• Chorionic Gonadotropin

Available Dosage Forms:

• Powder for Solution


• Solution

Therapeutic Class: Endocrine-Metabolic Agent

Pharmacologic Class: Gonadotropin

Uses For Novarel

Chorionic gonadotropin is a drug whose actions are almost the same as those of luteinizing hormone (LH), which is produced by the pituitary gland. It is a hormone also normally produced by the placenta in pregnancy. Chorionic gonadotropin has different uses for females and males.

In females, chorionic gonadotropin is used to help conception occur. It is usually given in combination with other drugs such as menotropins and urofollitropin. Many women being treated with these drugs usually have already tried clomiphene alone (e.g., Serophene) and have not been able to conceive yet. Chorionic gonadotropin is also used in in vitro fertilization (IVF) programs.

In males, LH and chorionic gonadotropin stimulate the testes to produce male hormones such as testosterone. Testosterone causes the enlargement of the penis and testes and the growth of pubic and underarm hair. It also increases the production of sperm.

Although chorionic gonadotropin has been prescribed to help some patients lose weight, it should never be used this way. When used improperly, chorionic gonadotropin can cause serious problems.

Chorionic gonadotropin is to be administered only by or under the immediate supervision of your doctor.

Before Using Novarel

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Chorionic gonadotropin, when used for treating cryptorchidism (a birth defect where the testes remain inside the body), has caused the sexual organs of some male children to develop too rapidly.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	X	Studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Asthma or


• Epilepsy (seizures) or


• Heart problems or


• Kidney problems or


• Migraine headaches—This medication may worsen these conditions.

• Cancer of the prostate or


• Precocious puberty (a condition that causes early puberty in boys before 9 years of age)—Increases in the amount of testosterone in the bloodstream may make these conditions worse.

• Cyst on ovary or


• Fibroid tumors of the uterus—Chorionic gonadotropin can cause further growth of cysts on the ovary or fibroid tumors of the uterus

• Unusual vaginal bleeding—Irregular vaginal bleeding is a sign that the endometrium is growing too much, of endometrial cancer, or of other hormone imbalances; the increases in estrogen production caused by ovulation can aggravate these problems of the endometrium. If other hormone imbalances are present, they should be treated before beginning ovulation induction

Proper Use of chorionic gonadotropin

This section provides information on the proper use of a number of products that contain chorionic gonadotropin. It may not be specific to Novarel. Please read with care.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For injection dosage form:
  
  • For treating men with problems related to low levels of male hormones:
    
    • Adults—1000 to 4000 Units injected into the muscle two to three times a week. You may need to receive this medicine for several weeks, months, or longer. If you are being treated for a low sperm count and have been on this medicine for six months, your doctor may give you another hormone medicine (menotropin or urofollitropin injection). You may need to receive both of these medicines together for up to twelve more months.
    
    
  
  
  • To help pregnancy occur in women:
    
    • Adults—5000 to 10,000 Units injected into the muscle on a day chosen by your doctor. The dose and day will depend on your hormone levels and the other medicines that you have been using.
    
    
  
  
  • For the treatment of cryptorchidism (condition where testes do not develop properly):
    
    • Children—1000 to 5000 Units injected into the muscle two to three times a week for up to ten doses.
    
    
  
  

Precautions While Using Novarel

It is very important that your doctor check your progress at regular visits to make sure that the medicine is working and to check for unwanted effects.

For women taking this medicine to become pregnant :

• Record your basal body temperature every day if told to do so by your doctor, so that you will know if you have begun to ovulate. It is important that intercourse take place around the time of ovulation to give you the best chance of becoming pregnant. Your doctor will likely want to monitor the development of the ovarian follicle(s) by measuring the amount of estrogen in your bloodstream and by checking the size of the follicle(s) with ultrasound examinations.

Novarel Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

For females onlyMore common

• Bloating (mild)


• stomach or pelvic pain

Less common or rare

• Abdominal or stomach pain (severe)


• bloating (moderate to severe)


• decreased amount of urine


• feeling of indigestion


• nausea, vomiting, or diarrhea (continuing or severe)


• pelvic pain (severe)


• shortness of breath


• swelling of feet or lower legs


• weight gain (rapid)

For boys onlyLess common

• Acne


• enlargement of penis and testes


• growth of pubic hair


• increase in height (rapid)

Frequency not determined

• difficult or labored breathing


• difficulty breathing


• flushing of skin


• hives or welts


• itching of skin


• large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, sex organs


• pain in chest, groin, or legs, especially the calves


• redness of skin


• severe, sudden headache


• skin rash


• slurred speech


• sudden loss of coordination


• sudden, severe weakness or numbness in arm or leg


• sudden, unexplained shortness of breath


• tightness in chest


• unusually warm skin


• vision changes


• wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Discouragement


• enlargement of breasts


• feeling sad or empty


• headache


• irritability


• lack of appetite


• loss of interest or pleasure


• pain at place of injection


• trouble concentrating


• trouble sleeping


• tiredness

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

For females onlyLess common or rare

• Abdominal or stomach pain (severe)


• bloating (moderate to severe)


• decreased amount of urine


• feeling of indigestion


• nausea, vomiting, or diarrhea (continuing or severe)


• pelvic pain (severe)


• shortness of breath


• weight gain (rapid)

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Novarel side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Novarel resources

• Novarel Side Effects (in more detail)
• Novarel Use in Pregnancy & Breastfeeding
• Novarel Drug Interactions
• Novarel Support Group
• 0 Reviews for Novarel - Add your own review/rating

• Novarel Prescribing Information (FDA)


• Novarel MedFacts Consumer Leaflet (Wolters Kluwer)


• Hcg Consumer Overview


• Ovidrel Prescribing Information (FDA)


• Ovidrel Monograph (AHFS DI)


• Ovidrel MedFacts Consumer Leaflet (Wolters Kluwer)


• Pregnyl Prescribing Information (FDA)

Compare Novarel with other medications

• Female Infertility
• Hypogonadism, Male
• Ovulation Induction
• Prepubertal Cryptorchidism

Nasalcrom Child nasal

Generic Name: cromolyn sodium (nasal) (KRO mo lin SO dee um)

Brand Names: Nasalcrom, Nasalcrom Child

What is Nasalcrom Child (cromolyn sodium (nasal))?

Cromolyn sodium is an anti-inflammatory medication. It works by preventing the release of substances in the body that cause inflammation.

Cromolyn sodium nasal is used to prevent allergy symptoms such as runny nose, stuffy nose, sneezing, itching, and post-nasal drip.

Cromolyn sodium nasal will not treat allergy symptoms that have already begun. The medication works best if used at least 1 week before you come into contact with things you are allergic to (pollen, dust, pets, etc).

Cromolyn sodium nasal will not treat the symptoms of asthma, sinus infections, or the common cold.

Cromolyn sodium nasal may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Nasalcrom Child (cromolyn sodium (nasal))?

You should not use this medication if you are allergic to cromolyn sodium.

Before you use cromolyn sodium nasal, tell your doctor if you have asthma, drug allergies, or polyps in your nose.

Cromolyn sodium nasal will not treat allergy symptoms that have already begun. The medication works best if used at least 1 week before you come into contact with things you are allergic to (pollen, dust, pets, etc).

Stop using this medication and call your doctor if you have severe burning, stinging, or irritation in your nose, nosebleeds, sinus pain, sores in your nose, wheezing, chest tightness, fever, or green/yellow mucus from your nose.

Do not use cromolyn sodium nasal more than 6 times in a 24-hour period. Do not use this medication for longer than 12 weeks unless your doctor has told you to.

What should I discuss with my healthcare provider before using Nasalcrom Child (cromolyn sodium (nasal))?

You should not use this medication if you are allergic to cromolyn sodium.

If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you use cromolyn sodium nasal, tell your doctor if you have:

• 
  

  asthma;

  
  


• 
  

  drug allergies; or

  
  


• 
  

  polyps in your nose.

  
  

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether cromolyn sodium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use Nasalcrom Child (cromolyn sodium (nasal))?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the directions on your prescription label.

This medicine is usually given as 1 spray into each nostril every 4 to 6 hours during allergy season or within 1 week before you will be exposed to an allergen. Follow your doctor's instructions.

Do not use cromolyn sodium nasal more than 6 times in a 24-hour period. Do not use this medication for longer than 12 weeks unless your doctor has told you to.

To use the nasal spray:

• 
  

  Blow your nose gently before each use.

  
  


• 
  

  Keeping your head upright, insert just the tip of the spray bottle into your nostril. Hold your other nostril closed with one finger. Spray the medicine into the nostril while inhaling, then sniff deeply a few times to make sure the medicine gets up into your nasal passages.

  
  


• 
  

  Repeat these steps in your other nostril.

  
  


• 
  

  After using the nasal spray, rinse the tip with hot water or wipe it with a clean tissue and recap. Avoid getting water into the nasal spray tip.

  
  

It may take up to 2 weeks of using this medicine before you get the full effect. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 2 weeks of treatment.

Store cromolyn sodium at room temperature away from moisture, heat, and light. Keep the bottle capped when not in use.

What happens if I miss a dose?

Use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and use the medicine at the next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

What should I avoid while using Nasalcrom Child (cromolyn sodium (nasal))?

Avoid getting this medication in your eyes. If this does happen, rinse with water.

Nasalcrom Child (cromolyn sodium (nasal)) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives or itching; difficulty breathing; severe dizziness; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor if you have any of these serious side effects:

• 
  

  severe burning, stinging, or irritation in your nose;

  
  


• 
  

  nosebleeds, sinus pain, or sores in your nose;

  
  


• 
  

  wheezing, tight feeling in your chest; or

  
  


• 
  

  fever, green or yellow mucus from the nose.

  
  

Less serious side effects may include mild burning or stinging inside your nose after use.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Nasalcrom Child (cromolyn sodium (nasal))?

There may be other drugs that can interact with cromolyn sodium nasal. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Nasalcrom Child resources

• Nasalcrom Child Side Effects (in more detail)
• Nasalcrom Child Use in Pregnancy & Breastfeeding
• 0 Reviews for Nasalcrom Child - Add your own review/rating

Compare Nasalcrom Child with other medications

• Hay Fever

Where can I get more information?

• Your pharmacist can provide more information about cromolyn sodium nasal.

See also: Nasalcrom Child side effects (in more detail)

gonadorelin injectable

Generic Name: gonadorelin (injectable) (gon ah doe REH lin)

Brand names: Factrel, Lutrepulse

What is gonadorelin?

Gonadorelin is a man-made protein that is like a hormone in the body called gonadotropin-releasing hormone (GnRH). GnRH causes the pituitary gland to release other hormones including luteinizing hormone (LH) and follicle-stimulating hormone (FSH). LH and FSH are important for proper development in children and fertility in adults.

Gonadorelin is used to test how well the hypothalamus and pituitary glands are working.

Gonadorelin may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about gonadorelin?

Before using gonadorelin, tell your doctor if you have any other medical conditions or if you take any medications, including herbal products. You may not be able to take gonadorelin, or you may require a dosage adjustment or special monitoring.

What should I discuss with my healthcare provider before taking gonadorelin?

Before using gonadorelin, tell your doctor if you have any other medical conditions or if you take any medications, including herbal products. You may not be able to take gonadorelin, or you may require a dosage adjustment or special monitoring.

Gonadorelin is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take gonadorelin without first talking to your doctor if you are pregnant. It is not known whether gonadorelin passes into breast milk. Do not take gonadorelin without first talking to your doctor if you are breast-feeding a baby.

How should I take gonadorelin?

Gonadorelin is administered by a healthcare professional as a subcutaneous (under the skin) or intravenous (into a vein) injection.

Blood samples will be drawn before and after administration of gonadorelin to measure hormone levels in the body.

Your healthcare provider will store gonadorelin as directed by the manufacturer. If you are storing gonadorelin at home, your healthcare provider will provide storage instructions.

What happens if I miss a dose?

Missing a dose of gonadorelin should not occur as it is used for testing purposes only.

What happens if I overdose?

An overdose of gonadorelin is unlikely to threaten life. Notify your doctor immediately or call an emergency room or poison control center for advice if an overdose is suspected.

Symptoms of a gonadorelin overdose are not known.

What should I avoid while taking gonadorelin?

There are no restrictions on food, beverages, or activity during treatment with gonadorelin unless otherwise directed by your doctor.

Gonadorelin side effects

If you experience a rare allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives) to gonadorelin, seek emergency medical attention.

Other less serious side effects may also occur. Notify your doctor if you experience

• 
  

  headache;

  
  


• 
  

  flushing;

  
  


• 
  

  nausea or abdominal discomfort;

  
  


• 
  

  dizziness or lightheadedness;

  
  


• 
  

  pain, swelling, or itching at the injection site; or

  
  


• 
  

  skin rash.

  
  

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Gonadorelin Dosing Information

Usual Adult Dose for Gonadotropin Deficiency:

0.1 mg injected once subcutaneously or intravenously as a single dose.

Usual Adult Dose for Amenorrhea:

5 mcg every 90 minutes (range of 1 to 20 mcg) delivered intravenously by a pump over 1 minute, every ninety minutes for 21 days.

What other drugs will affect gonadorelin?

Other medicines that affect hormone levels in the body may affect test results following treatment with gonadorelin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products during treatment with gonadorelin.

More gonadorelin resources

• Gonadorelin Side Effects (in more detail)
• Gonadorelin Use in Pregnancy & Breastfeeding
• Gonadorelin Drug Interactions
• Gonadorelin Support Group
• 0 Reviews for Gonadorelin - Add your own review/rating

Compare gonadorelin with other medications

• Amenorrhea
• Gonadotropin Deficiency

Where can I get more information?

• Your pharmacist has additional information about gonadorelin written for health professionals that you may read.

What does my medication look like?

Gonadorelin is available with a prescription under the brand name Factrel. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

See also: gonadorelin side effects (in more detail)

nitroglycerin transdermal

Generic Name: nitroglycerin (transdermal) (NYE troe GLIS er in)

Brand Names: Minitran, Nitrek, Nitro TD Patch-A, Nitro-Dur

What is nitroglycerin transdermal?

Nitroglycerin is in a group of drugs called nitrates. Nitroglycerin dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.

Nitroglycerin transdermal is used to prevent attacks of chest pain (angina).

Nitroglycerin transdermal may also be used for purposes not listed in this medication guide.

What is the most important information I should know about nitroglycerin transdermal?

You should not use this medication if you are allergic to nitroglycerin, isosorbide mononitrate (Imdur), or isosorbide dinitrate (BiDil, Isordil).

Before using nitroglycerin transdermal, tell your doctor if you have congestive heart failure, low blood pressure, glaucoma, anemia, or a history of heart attack, stroke, or head injury.

Do not use this medication to treat an angina attack that has already begun. It will not work fast enough.

Nitroglycerin transdermal can cause severe headaches, especially when you first start using it. Do not stop using the skin patches, and ask your doctor before using any headache pain medication.

Nitroglycerin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Call your doctor at once if you have a serious side effect such as worsening chest pain, pain spreading to the arm or shoulder, nausea, vomiting, sweating, blurred vision and dry mouth, or fainting. Drinking alcohol can increase certain side effects of nitroglycerin. The nitroglycerin transdermal patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test.

What should I discuss with my healthcare provider before using nitroglycerin transdermal?

You should not use this medication if you are allergic to nitroglycerin, isosorbide mononitrate (Imdur), or isosorbide dinitrate (BiDil, Isordil). Do not use nitroglycerin transdermal if you are allergic to any type of adhesive on a bandage or other transdermal skin patch.

To make sure you can safely use nitroglycerin, tell your doctor if you have any of these other conditions:

• 
  

  congestive heart failure;

  
  


• 
  

  a history of heart attack, stroke, or head injury;

  
  


• 
  

  low blood pressure;

  
  


• 
  

  glaucoma; or

  
  


• 
  

  anemia (lack of red blood cells).

  
  

FDA pregnancy category C. It is not known whether nitroglycerin will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether nitroglycerin transdermal passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use nitroglycerin transdermal?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Do not use nitroglycerin transdermal to treat an angina attack that has already begun. It will not work fast enough. Your doctor may prescribe an oral form of nitroglycerin (tablet, capsule, spray) to treat an angina attack. Talk with your doctor if any of your medications do not seem to work as well in treating or preventing angina attacks.

The nitroglycerin transdermal skin patch is usually worn for 12 to 14 hours and then removed. A new patch is put on after a "patch-free" period of 10 to 12 hours. Your doctor may want you to wear the patch for longer or shorter periods of time. Follow your doctor's instructions carefully.

Apply the skin patch to a clean, dry, hairless area of the body, below your neck and above your knees or elbows. To remove any hair from these skin areas, clip the hair short but do not shave it.

Press the patch onto the skin and press it down firmly with your fingers. Make sure it is well sealed around the edges.

Wash your hands after applying a nitroglycerin transdermal skin patch.

If the patch falls off, try sticking it back on. If you replace the patch with a new one, leave it on only for the rest of your wearing time. Do not change your patch removal schedule.

After removing a skin patch fold it in half, sticky side in, and throw it away in a place where children or pets cannot get to it. Keep both used and unused nitroglycerin skin patches out of the reach of children or pets. Do not stop using this medication without your doctor's advice, even if you feel better. You may have increased angina attacks if you stop using the medication suddenly.

If you need to have any type of surgery or dental work, tell the surgeon or dentist ahead of time that you are using nitroglycerin transdermal.

The nitroglycerin transdermal patch may burn your skin if you wear the patch during an MRI (magnetic resonance imaging). Remove the patch before undergoing such a test.

Tell any doctor or other healthcare provider who treats you that you are using nitroglycerin transdermal. If you need emergency heart resuscitation, your family or caregivers should tell emergency medical personnel if you are wearing a nitroglycerin skin patch. The patch should be removed before any electrical equipment (such as a defribrillator) is used on you.

Store at room temperature, away from moisture and heat. Keep each skin patch in its sealed pouch until you are ready to use it.

What happens if I miss a dose?

Apply a patch as soon as you remember, and keep it on for the rest of your wearing time without changing your patch removal schedule. If you miss a dose and it is almost time to apply your next patch, wait until then to apply the patch and skip the missed dose.

Do not use extra patches to make up a missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include a severe throbbing headache, confusion, fever, fast or pounding heartbeats, dizziness, vision problems, nausea, vomiting, bloody diarrhea, trouble breathing, cold or clammy skin, feeling light-headed, fainting, seizure (convulsions), or blue-colored skin, lips, or nails.

What should I avoid while using nitroglycerin transdermal?

Avoid using nitroglycerin transdermal on irritated or broken skin.

Nitroglycerin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Drinking alcohol can increase certain side effects of nitroglycerin.

Nitroglycerin transdermal side effects

Nitroglycerin transdermal can cause severe headaches, especially when you first start using it. These headaches may gradually become less severe as you continue to use nitroglycerin transdermal. Do not stop using the medication. Ask your doctor before using any headache pain medication.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  worsening chest pain, slow heart rate;

  
  


• 
  

  feeling like you might pass out;

  
  


• 
  

  chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

  
  


• 
  

  fast or pounding heartbeats; or

  
  


• 
  

  blurred vision and dry mouth.

  
  

Less serious side effects may include:

• 
  

  mild skin rash or itching;

  
  


• 
  

  warmth, redness, or tingly feeling under your skin;

  
  


• 
  

  nausea, vomiting, upset stomach; or

  
  


• 
  

  feeling nervous, weak, or dizzy.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Nitroglycerin Dosing Information

Usual Adult Dose for Angina Pectoris:

For relief of acute anginal attack:

Lingual spray: 1 to 2 sprays (0.4 to 0.8 mg) onto or under the tongue every 3 to 5 minutes as needed, up to 3 sprays in 15 minutes. If pain persists after the maximum number of doses, prompt medical attention is recommended.

Sublingual tablet: 0.3 to 0.6 mg dissolved under the tongue or in the buccal pouch every 5 minutes as needed, up to 3 doses in 15 minutes. If pain persists after the maximum number of doses, prompt medical attention is recommended.

IV continuous infusion (via non PVC tubing): 5 mcg/min initially, increased by 5 mcg/min every 3 to 5 minutes as needed up to 20 mcg/min, then gradually by 10 and then 20 mcg/min if needed, up to a usual maximum of 200 and generally no more than 400 mcg/min. Starting dosages of 25 mcg/min or higher have been used with PVC administration sets.

Usual Adult Dose for Angina Pectoris Prophylaxis:

Lingual spray: 1 to 2 sprays (0.4 to 0.8 mg) onto or under the tongue 5 to 10 minutes prior to engaging in activities which might precipitate an acute attack

Sublingual tablet: 0.3 to 0.6 mg dissolved under the tongue or in the buccal pouch 5 to 10 minutes prior to engaging in activities which might precipitate an acute attack

Topical ointment: 1/2 inch initially, applied to a non hairy area of the trunk every 6 to 8 hours during waking hours (2 times a day); titrate as needed and tolerated. If angina occurs while the ointment is in place, the dose should be increased; if angina occurs several hours after application, the dosing frequency should be increased. Usual range is 1/2 to 2 inches (7.5 to 30 mg) every 8 hours, typically applied to 36 square inches of truncal skin.

Transdermal patch: 0.1 to 0.4 mg/hr patch applied to a dry and hairless area of the upper arm or body for 12 to 14 hours per day; titrate as needed and tolerated up to 0.8 mg/hr. Application sites should be rotated to avoid skin irritation.

Transmucosal (buccal) tablet: 1 mg dissolved between the lip and gum above the upper incisors or between the cheek and gum every 3 to 5 hours during waking hours (approximately 3 times a day); titrate as needed and tolerated. If angina occurs while a tablet is in place, the dose should be increased to the next strength; if angina occurs after dissolution of tablet, the dosing frequency should be increased. Usual maintenance dosage is 2 mg three times a day. If an acute attack occurs while a tablet is in place, another tablet may be administered on the opposite side from the one already in place. Sublingual nitroglycerin is recommended if prompt relief is not attained.

Oral: 2.5 every 8 to 12 hours; titrate as needed and tolerated up to 9 mg every 8 to 12 hours

Because tolerance to nitroglycerin may develop if plasma levels are maintained continuously, a nitrate free interval of 10 to 12 hours per day may be appropriate during chronic prophylaxis of angina pectoris. However, clinical studies suggest that such intermittent use may be associated with hemodynamic rebound during drug withdrawal and decreased exercise tolerance during the latter part of the nitrate free interval. Although the clinical relevance of this observation is unknown, a potentially increased risk of anginal attack during the nitrate free interval should be considered. Therefore, dosing regimens should be carefully individualized to each patient. Other antianginal drugs such as beta-blockers and calcium channel blockers may be prescribed to reduce the risk of aggravating myocardial ischemia during the drug free intervals.

Usual Adult Dose for Congestive Heart Failure:

Topical ointment: 1/2 inch initially, applied to a non hairy area of the trunk every 6 to 8 hours during waking hours (2 times a day); titrate as needed and tolerated. Usual range is 1/2 to 2 inches (7.5 to 30 mg) every 8 hours, typically applied to 36 square inches of truncal skin.

Transdermal patch: 0.1 to 0.4 mg/hr patch applied to a dry and hairless area of the upper arm or body for 12 to 14 hours per day; titrate as needed and tolerated up to 0.8 mg/hr. Application sites should be rotated to avoid skin irritation.

Transmucosal (buccal) tablet: 1 mg dissolved between the lip and gum above the upper incisors or between the cheek and gum every 3 to 5 hours during waking hours (approximately 3 times a day); titrate as needed and tolerated. Usual maintenance dosage is 2 mg three times a day.

Oral: 2.5 every 8 to 12 hours; titrate as needed and tolerated up to 9 mg every 8 to 12 hours

Usual Adult Dose for Myocardial Infarction:

For the initial 24 to 48 hours after an acute myocardial infarction:

IV continuous infusion (via non PVC tubing): 5 mcg/min initially, increased by 5 mcg/min every 3 to 5 minutes as needed up to 20 mcg/min, then gradually by 10 and then 20 mcg/min if needed up to a usual maximum of 200 and generally no more than 400 mcg/min. Starting dosages of 25 mcg/min or higher have been used with PVC administration sets.

Usual Adult Dose for Hypertension:

IV continuous infusion (via non PVC tubing): 5 mcg/min initially, increased by 5 mcg/min every 3 to 5 minutes as needed up to 20 mcg/min, then gradually by 10 and then 20 mcg/min if needed up to a usual maximum of 100 mcg/min. Starting dosages of 25 mcg/min or higher have been used with PVC administration sets.

Usual Adult Dose for Anal Fissure and Fistula:

For the treatment of moderate to severe pain associated with chronic anal fissure:
Apply 1 inch of ointment (375 mg of ointment equivalent to 1.5 mg of nitroglycerin) intra anally every 12 hours for up to 3 weeks.

Usual Pediatric Dose for Hypertension:

Perioperative hypertension or induction of intraoperative hypotension:

IV continuous infusion: 0.25 to 0.5 mcg/kg/min initially, increase by 0.5 to 1 mcg/kg/min every 3 to 5 minutes as needed up to 5 mcg/kg/min. Usual dose is 1 to 3 mcg/kg/min, but doses as high as 20 mcg/kg/min have been used.

What other drugs will affect nitroglycerin transdermal?

Tell your doctor about all other medications you use, especially:

• 
  

  blood pressure medication or diuretics (water pills);

  
  


• 
  

  cold or allergy medicines, diet pills, or over-the-counter pain medicine such as ibuprofen (Advil, Motrin) or naproxen (Aleve);

  
  


• 
  

  an erectile dysfunction medication such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra);

  
  


• 
  

  migraine headache medication such as ergotamine (Ergomar, Cafergot, Migergot), dihydroergotamine (D.H.E. 45, Migranal), or methylergonovine (Methergine);

  
  


• 
  

  a beta-blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others; or

  
  


• 
  

  heart or blood pressure medicine such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta), diltiazem (Cartia, Cardizem), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others.

  
  

This list is not complete and other drugs may interact with nitroglycerin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More nitroglycerin resources

• Nitroglycerin Side Effects (in more detail)
• Nitroglycerin Dosage
• Nitroglycerin Use in Pregnancy & Breastfeeding
• Drug Images
• Nitroglycerin Drug Interactions
• Nitroglycerin Support Group
• 6 Reviews for Nitroglycerin - Add your own review/rating

Compare nitroglycerin with other medications

• Anal Fissure and Fistula
• Angina
• Angina Pectoris Prophylaxis
• Heart Attack
• Heart Failure
• High Blood Pressure
• Raynaud's Syndrome

Where can I get more information?

• Your pharmacist can provide more information about nitroglycerin transdermal.

See also: nitroglycerin side effects (in more detail)

Thera-Tabs

Generic Name: Multivitamins (MUL-ti-VYE-ta-mins)
Brand Name: Examples include Stress-600 and Thera-Tabs

Thera-Tabs is used for:

Treating or preventing low levels of vitamins in the body. It may also be used for other conditions as determined by your doctor.

Thera-Tabs is a vitamin supplement. It works by providing extra vitamins to the body.

Do NOT use Thera-Tabs if:

• you are allergic to any ingredient in Thera-Tabs

Contact your doctor or health care provider right away if any of these apply to you.

Before using Thera-Tabs:

Some medical conditions may interact with Thera-Tabs. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Thera-Tabs.

Ask your health care provider if Thera-Tabs may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Thera-Tabs:

Use Thera-Tabs as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Thera-Tabs by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• If you miss a dose of Thera-Tabs, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Thera-Tabs.

Important safety information:

• Do not take large doses of vitamins while you use Thera-Tabs unless your doctor tells you to.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Thera-Tabs while you are pregnant. It is not known if Thera-Tabs is found in breast milk. If you are or will be breast-feeding while you use Thera-Tabs, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Thera-Tabs:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with Thera-Tabs. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Thera-Tabs side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include nausea; vomiting.

Proper storage of Thera-Tabs:

Store Thera-Tabs at room temperature. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Thera-Tabs out of the reach of children and away from pets.

General information:

• If you have any questions about Thera-Tabs, please talk with your doctor, pharmacist, or other health care provider.


• Thera-Tabs is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Thera-Tabs. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Thera-Tabs resources

• Thera-Tabs Side Effects (in more detail)
• Thera-Tabs Use in Pregnancy & Breastfeeding
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